Now that the products are being official shown in the USA, we can be more forthcoming with information.
If you are using the tool program to configure the device it depends on the model selected. The SCX20 (NMEA 2000) would be placed on a standard bus and the PC would need a proper interface to also connect to the bus so they can communicate. This is typically a kvaser or similar CANbus interface for the PC to use. If using the SCX21, then the PC will need a RS422 converter to interface to the PC via typically the USB port. (like the pn 422-USB-CBL).